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At present, the main body of high-rise or super-high-rise buildings mostly adopt steel structure, and the fire resistance of steel structure is poor. If fire protection is not adopted, if the fire is damaged, the structure will be destroyed easily. "911" The best example. Using silicon dioxide aerogels insulation composite material for steel structure fireproofing can not only prolong the fireproof time, but also will not release harmful substances to the human body under the high temperature, and belongs to the whole green fireproof material, so it is favored by people. Qinghai-Tibet Railway is the world's highest altitude, the longest line of the plateau railway, its construction to promote economic exchanges, enhance national unity, safeguard national unity, consolidate national defense security and maintain social stability is extremely important strategic significance. However, the construction of the railway on the plateau is confronted with the two major problems of climate and permafrost. With the change of temperature and the rise and fall of temperature, the permafrost will freeze and swell and sink, which will bring adverse impact on the construction. It is also one of the causes of damage to engineering structures in permafrost regions. The development of a new type of silicon dioxide aerogels with high efficiency thermal insulation has broad prospects for solving this problem. aerogels glass, as a new building material, has good thermal stability, thermal shock resistance and thermal insulation, can replace the traditional mineral wool, so that the house is both insulated and warm. If it is used in high-rise buildings, can replace the general curtain wall glass, greatly reducing the building weight, and can play a role in fire prevention. In addition, silicon dioxide aerogels insulation can be used as high-efficiency heat insulation and sound insulation material because of its low apparent density, thermal conductivity and high temperature resistance.

The potential for environmental and health effects of silicon dioxide nanoparticles (SiNPs) has increased, due to their increased use in products and applications. The biological efficacy of a group of similarly sized amorphous SiNPs was investigated in various cells to examine the effects of physicochemical and biological factors on their toxicity. Cells were measured for LDH and ATP, BrdU incorporation, day of blasts in human epithelial A549, human THP-I, and mouse J774A.1 macrophage cells exposed to suspension of SiNPs for 24 hours to 5-15, 10-20 and 12 nm Green reduction and cytokine release, reference granules. SiNPs were characterized in the dry state and in the suspensions to determine their physicochemical properties. The dose-response data is reduced to a particle potency estimate to facilitate comparison of multiple endpoints in biological effects in cells. Mouse macrophages are most sensitive to SiNP exposure. Single cell lines are cytotoxic, whereas cytokine responses are different and are supported by cell type-specific differences in inflammation-related pathways. SiNP (12 nm), the most cytotoxic and proinflammable nanoparticles have the highest surface acidity and dry agglomerate size, as well as the lowest trace metal and organic content, minimum surface area in suspension and agglomerate size. The surface acidity of the particles appears to be the most important determinant of the overall biological activity of this group of nanoparticles. The integration of bio-potency estimates in combination with nanoparticle characterization allows for a comprehensive determination of the cellular reactivity of SiNP. The method shows a desire to be a useful tool for first-order screening for SiNP toxicity.



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