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Silicon Dioxide is widely used in many field. Many food contain Silicon Dioxide, and it contains various amounts of Silicon Dioxide, for example: potatoes 10.1, milk 2.1, drinking-water 7.1, mineral-water 22.5, beer 131 gamma SiO2 per g or cm3. Silicon Dioxide is also used in medical. Silica, silicic acid and the calcium, magnesium and aluminium salts occur ubiquitously in the environment and some have been used for many years medically. Very small amounts of silica are normally present in all body tissues but there is no evidence that they play any physiological role.

The normal level of Silicon Dioxide cotain in human body: The normal level of silicic acid in human blood is below 1 μg Silicon Dioxide  SiO2/cm3; the concentration in the corpuscles is practically the same as that in the plasma. Silicic acid is present in plasma in a molybdate reactive form and is not bound to protein or any other substance of high molecular weight. Ingested monomeric silicic acid rapidly penetrates the intestinal wall and becomes distributed throughout the whole extra-cellular fluid. It enters the blood corpuscles at a slower rate. Silicic acid is a normal constituent of the urine, where it is found as early as a few days after birth. The amount excreted in the urine, which varies considerably according to the diet, is in the order of 10 to 30 mg per day. 

The silica content of human tissue varies from 10 to 200 mg/100 g dry weight (spleen 15 mg,lung 140 mg). Excessive intake of Silicon Dioxide is harmful to organisms. Here is an experiment. Ten gamma monomeric Silicon Dioxide SiO2/cm3 was shown in vitro to damage the enzymes of isolated mitochondria in rat liver. Very small amounts of silica are normally present in all body tissues. Recently it was found that silicon meets the criteria for an essential trace element in the chick (see short-term studies).  Administration of 5 g of the siliceous materials listed below in 20 ml of milk by stomach tube to cats showed the following urinary excretion within 120 hours; silicic acid (fresh) 43.3, calcium silicate 37.2, magnesium trisilicate 34.1, silicic acid (moist) 29.0,  SiO2 (quarz) (air sediment very fine) 20.8, magnesium silicates (talc) 9.2, diatomaceous earth 8.8 and calcium silico aluminate hydrate (kaolin) 7.6 mg SiO2.



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